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*C clonorchiasis, 0 opisthorchiasis. *C clonorchiasis, 0 opisthorchiasis. and Harinasuta, 1980 Chen et al., 1983 Jong et al., 1985 Pungpak et al., 1983 Rim et al., 1981 Yangco et al., 1987) (Table 17.3). Efficacy rates are excellent, ranging from 86 to 100 with 75mg kg day divided into three doses for 1 day. By comparison, only 8 of C. sinensis infections resolved in a placebo group at 60 days (Jong et al., 1985). For C. sinensis, doses of less than 75 mg kg day decrease the efficacy (cure rate...

Taenia saginata

Symptomatology in Taenia carriers is vague and may include abdominal pain, nausea, dizziness, headache, weight loss, increased appetite, pruritus ani and excitation. Presence of the tapeworm can often be detected by the carrier after observing proglottids in the stool or active migration of segments through the anus. It should be stressed that many infections may go undetected. T. saginata should be suspected in a patient who ingests raw beef and who describes elimination of tapeworm segments...

Clinical Features

Acute and Indeterminate Phases of Chagas' Disease The first sign of acute T. cruzi infection can be a chagoma, which is an indurated and erythema-tous inflammatory lesion at the site where the parasite entered a week or two earlier (Rassi, 1979). If the parasite enters through a conjunctiva, the patient may develop unilateral and painless periorbital edema, which is called the Romana sign (Figure 14b.5). Spread of the parasites from the site of initial multiplication may be accompanied by fever...

Treatment

The major advance in the treatment of schisto-somiasis has been the development of praziquantel Cioli et al., 1995 . Until the 1960s, the only effective schistosomicidal agents available were the intravenous antimonials. The toxicity of antimonials was a major limitation, especially for mass therapy. Most of these earlier drugs should not be considered as a treatment option Shekhar, 1991 . Praziquantel is currently the drug of choice for all human schistosomes. The dosage is adjusted for...