AKA: Oxicebral.

Made from an extract of the periwinkle plant.

Effects: A vasodilator (improves blood flow to the brain and enhances the brain's utilization of oxygen). Users claim it improves memory and cognition, but sufficient scientific research is lacking for normal, healthy people.

Precautions: It may cause a reduction in white corpuscles and a degeneration of muscle tissue. In rare cases, it causes gastrointestinal problems.

Dosage: 60 mg/day in two divided doses.


AKA: Cavinton.

A close relative of vincamine believed to elicit more benefits and fewer side effects.

Effects: Reportedly a strong enhancer of memory and concentration. It improves the brain's metabolism by increasing the blood flow, speeding up the rate at which ATP is produced by the brain cells, and improving the use of glucose and oxygen in the brain. It is particularly effective for disorders caused by poor or impaired circulation, such as stroke, headaches, recurring dizziness, macular degeneration, and certain ear problems.

Precautions: No toxicity or contraindications. Side effects, which include dry mouth, hypotension, tachycardia, and weakness, are rare.

Dosage: 5 to 10 mg/day. It takes a year for the drug to reach its peak efficiency.

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