Tuberculous meningitis

- Isoniazid may produce peripheral neuropathy - protect with pyridoxine 50 mg daily. - Ethambutol may produce optic atrophy - check colour vision. - Streptomycin may cause 8th cranial nerve damage (vertigo and deafness). - Nausea, vomiting, abnormal liver function and skin rashes may occur with all antituberculous drugs. Intrathecal therapy. Since CSF penetration, especially with streptomycin, is poor, some recommend intrathecal treatment. Streptomycin 50 mg may be given daily or more...

Deafness Tinnitus And Vertigo

Deafness, tinnitus and vertigo result from disorders affecting the auditory and vestibular apparatus or their central connections transmitted through the VIII cranial nerve. MECHANISMS OF AUDITORY AND VESTIBULAR FUNCTION Auditory function the cochlea converts sound waves into action potentials in cochlear neurons. Sound waves are transmitted by the tympanic membrane and the ossicles to the oval window, setting up waves in the perilymph of the cochlea. The action of the waves on the spiral organ...